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Clinical Scientist

Waltham, MA | Full Time | Remote
22 Days Ago

Job Description

Xilio Therapeutics is a clinical-stage biotechnology company focused on harnessing the immune system to achieve deep and durable clinical responses to improve the lives of patients with cancer. We are using our proprietary geographically precise solutions (GPS) platform to rapidly engineer novel molecules, including cytokines and other biologics, that are designed to optimize their therapeutic index. These molecules are designed to localize activity within the tumor microenvironment without systemic effect, resulting in the potential to achieve enhanced anti-tumor activity. We are building a pipeline of tumor- selective, GPS-enabled cytokine and checkpoint inhibitor product candidates.

Xilio was founded in 2016 and recently completed its IPO, listing on the Nasdaq Global Select Market (Nasdaq: XLO). Xilio is headquartered in Waltham, MA.

Xilio offers the opportunity to work in an innovation driven, exciting biotechnology company doing ground-breaking work in the field of immuno-oncology. We offer a competitive compensation package including a base salary, annual bonus potential, stock options, 401k, healthcare benefits and paid time-off.

POSITION SUMMARY:

Xilio Therapeutics is looking for a Clinical Scientist who will be responsible for providing scientific support for clinical development activities for our clinical programs. You will play an integral role in clinical trial conduct and have accountability for clinical data and its quality.  The dynamics of a small team will allow high visibility and an opportunity to shape the clinical team strategy and involvement in the preparation of scientific manuscript and regulatory documents.

This position requires a strong scientific background preferably with a focus in Oncology and Immunology. You should be able to clearly communicate concepts and information both in writing and via formal presentations to scientific and medical experts both internal and external to the company. The Clinical Scientist should think creatively, function independently, have good strategic insights and have knowledge of the activities and procedures involved in clinical drug development.

The Clinical Scientist will report to the Vice President, Clinical Research and will collaborate closely with clinical operations, data management and biostatistics, clinical pharmacology and program management.

POSITION RESPONSIBILITIES:

  • In collaboration with VP, Clinical Research/Medical Monitors, provide strategic medical/scientific input and support to clinical development plans, clinical study protocols and other trial-related documents
  • Develop strong working relationships with external investigators and research personnel to ensure optimal clinical study design, execution, and reporting; and serve as the primary point of contact for clinical research sites
  • Serve as the clinical partner to clinical operations, data management, biostatistics and programming, and provide critical input in the development of statistical analysis plans and case report forms.
  • Lead medical data review and be responsible for data integrity
  • Collaborate with the clinical development team on the review, analysis, and interpretation of study results and assure appropriate data review and accurate data reporting
  • Spearhead analysis and interpretation of clinical trial data in preparation for the development of clinical trial reports, investigator brochures, annual safety reports publications and internal/external presentations
  • Provide support to advisory boards, consultant meetings and investigator meetings, including preparation and delivery of presentations.
  • Prepare data and contribute to scientific publications including posters, abstracts and manuscripts.
  • Provide scientific input to the efficacy and safety endpoints of the clinical trials.
  • Support the development of program documents, including the clinical sections of various regulatory documents such as clinical study reports, investigator brochures, annual reports and updates, and clinical sections of regulatory submissions to support product approvals.
  • Proactively seek out and recommend process improvements
  • Anticipate potential study problems and preparing contingency plans as needed. Communicate clearly and precisely with all levels of the company.

POSITION QUALIFICATIONS:

  • RN, MS, PhD or PharmD, or equivalent with clinical research experience.
  • At least 3-5 years of technical/operational experience in planning, executing, reporting and publishing clinical studies.
  • Demonstrated experience lead medical data review and ensuring data integrity.
  • Strong knowledge of oncology drug development required.
  • A strong scientific background with industry clinical research experience is required.
  • Thorough understanding of ICH, GCP, and relevant regulatory requirements.
  • Strong analytical and strategic thinking skills.
  • Experience with interacting with clinical investigators and medical experts.
  • Excellent verbal, written, and interpersonal communication skills (fluency in written and spoken English is required).
  • Ability and willingness to travel up to 10%.
  • Xilio Therapeutics strongly encourages all employees to be vaccinated against COVID-19.

Diversity, Equity and Inclusion

At Xilio Therapeutics, we foster a culture of equity, diversity and inclusion.  We consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law.  We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability who requires an accommodation with the hiring process or to perform any essential functions of the position for which you are applying, please reach out to careers@xiliotx.com.

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Skills for Clinical Scientist

The job skills required for Clinical Scientist include Presentation, Collaboration, Oncology, Innovation, clinical trial,and Pharmacology etc. Having related job skills and expertise will give you an advantage when applying to be a Clinical Scientist. That makes you unique and can impact how much salary you can get paid. Below are job openings related to skills required by Clinical Scientist. Select any job title you are interested in and start to search job requirements.

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Career Path for Clinical Scientist

The following is the career advancement route for Clinical Scientist positions, which can be used as a reference in future career path planning. As a Clinical Scientist, it can be promoted into senior positions as a Clinical Research Manager that are expected to handle more key tasks, people in this role will get a higher salary paid than an ordinary Clinical Scientist. You can explore the career advancement for a Clinical Scientist below and select your interested title to get hiring information.