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Automation Engineer
Krystal Biotech Pittsburgh, PA
Full Time | Contract Research 6 Months Ago
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Krystal Biotech is Hiring an Automation Engineer Near Pittsburgh, PA

Automation Engineer (Senior/Lead)

About Krystal Bio:

At Krystal Biotech, Inc., we bring together the brightest and most eager minds to relentlessly pursue the discovery, development and delivery of transformative medicines for people with serious and life-threatening genetic diseases. Founded in 2016, the Company is the leader in redosable gene therapy with prominent clinical and pre-clinical stage programs for dystrophic epidermolysis bullosa, TGM1-deficient ARCI, Netherton Syndrome, Cystic Fibrosis, alpha-1 antitrypsin deficiency, and is advancing research to apply our technology to these and other diseases. The Company’s innovation is fueled by visionary leadership within an entrepreneurial organizational structure with a robust pipeline of investigational medicine.

Our US headquarters is in Pittsburgh, PA with other offices located in Boston, MA and in Zug, Switzerland. For more information about the Company’s platform, commitment to patients and pipeline, please visit http://www.krystalbio.comand engage with us on Twitter and LinkedIn.

We have an exciting journey ahead and a tremendous opportunity for growth, and now is the time to make a meaningful impact on the lives of our patients!

Job Description Summary:

Krystal Biotech, Inc is seeking a highly motivated Automation Engineer to provide key support throughout the lifecycle for various manufacturing, laboratory, quality and research systems, as well as ensuring that infrastructure, physical and logical, and industrial automation software applications ensure and meet Krystal’s needs.

The Automation Engineer will develop automation solutions and participate in various phases of automation projects including the creation of design specifications, software configuration and testing, as well as commissioning and start-up of a variety of automated manufacturing processes. The ideal candidate will have a track record of proficiency with client relationships, control systems, troubleshooting and high intensity environments.

Primary Responsibilities:

  • Maintain existing control systems in reliable condition, propose improvements, and train and support manufacturing and maintenance personnel
  • Develop and drive overall hardware and data automation/collection strategy
  • Integrate local manufacturing equipment with plant wide SCADA/Historian systems
  • Perform predictive, preventative, and corrective maintenance efforts required to ensure efficient, reliable, and uninterrupted plant operations
  • Maintain and develop Automation Systems and their programs (Wonderware, Unicorn, iFIX, Allen Bradley)
  • Troubleshoot different controller software and hardware components
  • Oversee PID controls tuner and cascading controls
  • Conduct timely and competent root cause analyses. Recommend and implement innovative, efficient, and effective corrective actions resulting in stable and capable processes
  • Support validation and manufacturing projects
  • Scale hardware engineering prototypes from conception to higher manufacturing volumes
  • Design, build and test systems for our biomanufacturing infrastructure
  • Work with the teams to create new bioreactors, single-use assemblies, and automation systems
  • Work with other teams to track and evaluate critical process data to recommend continuous process improvement
  • Work with QA to perform and document the work
  • Awareness of and adherence to cGMP and GDP procedures and practices according to FDA regulations. Specifically, CFR Part 11 and Data Integrity
  • Other duties as assigned

Requirements and Desired Competencies:

  • Bachelors’ Degree in Science, Engineering, or related technical discipline
  • 5 years of experience as an Automation Engineer or related in a biotech, pharmaceutical, chemical, or similar R&D or manufacturing environment
  • 2 years of experience with developing and improving protocol methods for biotech or chemical process or testing equipment
  • Demonstrated background operating as lead/primary engineer with minimal oversight
  • Knowledge of Unicorn, Allen-Bradley PLC, iFix and iHistorian preferred
  • Experience using programming languages
  • Experience in creating workflows based on lab requirements
  • Experience with technical documentation such as process diagrams and system requirements
  • Familiarity with molecular biology and cell culture workflows
  • Experience integrating equipment with laboratory information management systems (LIMS) tools

Krystal Biotech, Inc. is an Equal Employment Opportunity and Affirmative Action Employers. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender perception or identity, national origin, age, marital status, protected veteran status, or disability status. Headhunters and recruitment agencies may not submit resumes/CVs through this Web site or directly to managers. Krystal Biotech, Inc. does not accept unsolicited headhunter and agency resumes. Krystal Biotech, Inc. will not pay fees to any third-party agency or company that does not have a signed agreement with Krystal Biotech, Inc. 

Job Summary

JOB TYPE

Full Time

INDUSTRY

Contract Research

POST DATE

09/17/2022

EXPIRATION DATE

12/14/2022

WEBSITE

krystalbio.com

HEADQUARTERS

SAN FRANCISCO, CA

SIZE

50 - 100

FOUNDED

2016

CEO

SUMA KRISHNAN

REVENUE

<$5M

INDUSTRY

Scientific Services

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