Overview

The Proteomics Core Facility (PCF) at the National Institute of Neurological Disorders and Stroke (NINDS) is seeking a dedicated and enthusiastic Biochemist. This is a full-time, on-site opportunity in Bethesda, MD.

Duties & Responsibilities

• Maintain and update accurate records of daily experiments and results including research documentation.
• Perform routine laboratory maintenance; ensure research supplies are kept stocked.
• Maintain and update laboratory notebooks and equipment.
• Prepare protein samples including in-gel, in-solution, on-beads digestion and 2D separation.
• Perform data acquisition on a Themo Fusion Lumos instrument and an Agilent 6230 LC-TOF instrument.
• Analyze data using Proteome Discoverer, Mascot, and MaxQuant software.
• Perform protein samples preparation for LC-MS/MS analysis.
• Report the results to core users.
• Present and communicate results with Project Team and staff.
• Collect, analyze, and interpret data for experimental results; prepare tables and figures.
• Evaluate new technologies and instruments resulting in proposals for new screening strategies and novel assay formats.
• Conduct routine maintenance of the equipment. Machines are under service contract.
• Maintain accurate research records digitally.
• Write manuscript for publications, in collaboration with other team members and outside collaborators.
• Write and review technical protocols and reports documenting analytical development studies pertaining to assigned work.
• Extract proteins from cells and tissues.
• Conduct routine and non-routine sample preparation/extraction methods for a variety of biological matrices including but not limited to plasma, urine, skeletal muscle, and brain tissue.
• Prepare tables, figures, and experimental details for publications and present results at conferences.
• Analyze the experiment results and present findings in project meetings, laboratory, and outside meetings.
• Work with staff in the design, implementation, interpretation, and reporting of bioanalytical method development and sample analysis.

#SOAR

Requirements

• Master’s degree in Biochemical Sciences
• At least 1 year of experience
• Hands on experience in Mass Spectrometry-based proteomic analysis
• Mass Spectrometry
• High-Performance Liquid Chromatography
• Matrix assisted laser desorption ionization (MALDI)
• MaxQuant
• Proteome Discoverer
• Mascot

Company Description

Dovel Technologies and its Family of Companies (Medical Science & Computing and Ace Info Solutions) was acquired in October 2021.

Guidehouse is a leading global provider of consulting services to the public sector and commercial markets, with broad capabilities in management, technology, and risk consulting. By combining our public and private sector expertise, we help clients address their most complex challenges and navigate significant regulatory pressures focusing on transformational change, business resiliency, and technology-driven innovation. Across a range of advisory, consulting, outsourcing, and digital services, we create scalable, innovative solutions that help our clients outwit complexity and position them for future growth and success. The company has more than 12,000 professionals in over 50 locations globally. Guidehouse is a Veritas Capital portfolio company, led by seasoned professionals with proven and diverse expertise in traditional and emerging technologies, markets, and agenda-setting issues driving national and global economies.

Guidehouse is an Equal Employment Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, ancestry, citizenship status, military status, protected veteran status, religion, creed, physical or mental disability, medical condition, marital status, sex, sexual orientation, gender, gender identity or expression, age, genetic information, or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance, including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities or to apply for a position, and you require accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at RecruitingAccommodation@guidehouse.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse, and Guidehouse will not be obligated to pay a placement fee.