Company Overview

Cell Signaling Technology, Inc. (CST) is a private, family owned, worldwide leader in the development and commercialization of antibodies, assays and research tools. As a company of scientists for scientists, we have developed XMT® technology, a proprietary method to develop exceptional monoclonal antibodies, PTMScan®, a technology to discover protein post-translational modifications, and PhosphoSitePlus®, an online resource for investigation of post-translational modifications. We are passionate about our role in contributing to the life science industry’s advancing of the human condition through accelerating the discovery and development of innovative therapies for human disease. We are fully committed to developing new research tools to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine.

Position Summary:

The Research Associate is a member of the Monoclonal Development team which is a core function for antibody development at CST. This individual will be responsible for screening XMT and mouse fusions to provide monoclonal antibody clones with the best utilities possible to be developed into final products. This position will focus on an early step in our product development process and will enable broad exposure to the full monoclonal antibody development process.

Responsibilities:

• Contribute to team’s goal of achieving highest possible screen success rate for XMT and mouse hybridoma as defined by percentage of XMT/mouse fusions of cloning requests filed by Antibody Discovery Verticals
• Effectively clone and release mouse hybridoma clone cultures to Antibody Production Group by following established standard operating procedures (SOPs) within service level agreement expectations
• Take over XMT or mouse fusion cultures from XMT or fusion performer
• Feed cultures to maintain optimal cell growth conditions to obtain maximum number of XMT or fusion colonies
• Maintain appropriate CO2 levels, temperature, and water level of assigned incubators
• Conduct periodic cleaning and decontamination of assigned biosafety cabinet and incubator(s) to ensure that cultures are free of microorganism contamination
• Release clone cultures at optimal health conditions and sufficient cell numbers to requestors including transferring requested frozen XMT to the Recombinant Cloning Group
• Provide XMT or fusion culture supernatants to Antibody Discovery Verticals and/or Clinical Application Testing Groups to facilitates western and applications testing
• Meet all internal service level agreements in turnaround time to release the requested clones to Recombinant Cloning Group and Antibody Production Group for further product development
• Purge unwanted frozen cultures in LN2 tanks and effectively manage existing LN2 storage spaces to ensure efficient productivity
• Participate in tissue culture room restocking and recycling
• Process and document resulting data in accordance with CST hard copy and electronic laboratory documentation requirements (e.g. notebooks, electronic LIMS, Jira, PDP, PLM, etc.) 

Requirements:

• Bachelors degree in a biological science (e.g. cell biology, immunology, biochemistry, molecular biology, or biotechnology)
• Basic understanding and working knowledge of experimental design and protocols
• Some hands on or class experience/exposure with tissue culture
• Computer proficiency including working knowledge of MS Office Suite, Google Docs, or related applications.
• Strong written and oral communication skills
• Demonstrated ability to work in a fast-paced, deadline-driven environment
• Proven effective team contributor
• Attention to detail
• Demonstrated organizational skills

Preferred:

• Bachelors degree in cell biology or immunology preferred
• 1 years of laboratory experience preferred
• Basic scientific understanding and application of fundamental biological experiments
• Knowledge in signal transduction is desirable
• Ability to analyze and problem solve
• Advanced Excel skills (e.g. function writing and page referencing)

What we offer....

At Cell Signaling Technology (CST) we recognize that people will always be our most important asset. Providing a safe, inclusive, and stimulating working environment that understands the importance of diversity, human dignity and meaningful work is as important as establishing company policies that incorporate excellent health insurance and pay benefits. We recognize that development of people is the key to their happiness and thus ensure every employee has impactful discussions with their manager and develops actionable performance and professional development plans. Lastly, we are committed to engaging and supporting our employees in committees and philanthropy that benefit their local communities and environment through community investment programs.

Benefits

• Medical (BCBS) and Dental (Delta Dental) plans paid at 90%
• Vision Insurance
• Life Insurance, Short and Long Term Disability
• Flexible Spending accounts
• 401(k) Plan with 6% match
• Tuition Reimbursement
• Generous PTO package
• Pet Insurance
• Employee Assistance Program
• Onsite Subsidized Cafeteria
• Free Parking

Our number one priority is the health and safety of our employees, their families, our communities, partners and customers. In order to promote that safety and well-being, we require that all US-based employees be fully vaccinated against COVID-19 by their start date. Applicants who receive an offer of employment who can provide documentation that the vaccine is medically contraindicated, or who object to vaccination due to a sincerely held religious belief, may make a request for exemption. We will consider requests for reasonable accommodations consistent with our policy, and where we are able to provide such accommodations without undue hardship to the company.

Cell Signaling Technology (CST) is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, status as a veteran or as a member of the military or status in any group protected by applicable federal or state laws.

AGENCIES

All resumes submitted by search firms/employment agencies to any employee at Cell Signaling Technology (CST) via email, the internet or in any form and/or method will be deemed the sole property of CST, unless such search firms/employment agencies were engaged by CST for this position and a valid agreement with CST is in place. In the event a candidate who was submitted outside of the CST agency engagement process is hired, no fee or payment of any kind will be paid.