Arrowhead Pharmaceuticals is a clinical-stage, Nasdaq-listed (ticker ARWR) company developing medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, our therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specified gene, thereby affecting the production of a specific protein. Our RNAi-based therapeutics are at the leading edge with the potential to bring life-changing treatments to patients.
Our Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. The TRiM platform builds on more than a decade of work on targeted RNA delivery and offers several advantages including simplified manufacturing and reduced costs; multiple routes of administration; and potential for improved safety.

The Position:

This position will ensure that the facility infrastructure and services are maintained and operated to support a fast-paced R&D and Business organization. The position opportunities include driving new facility start-up objectives and longer-term operation goals to ensure flexible, responsive, and reliable facilities.

Responsibilities:

• Plans, organizes, and supervises activities that are necessary for maintaining the physical structures, HVAC, mechanical, electrical systems, utilities, and grounds of the current SD office location in an operative and safe working condition
• Help coordinate the design, planning, construction, and moving into Arrowhead’s new San Diego location; will be responsible for the regular maintenance of the new site once fully operational
• Initiate and influence the integration of Safety/Facility policies and practices
• Manages all facility infrastructure requirements for research, development, and business management; this includes ensuring facility utilities are 100% operational and maintained to support laboratory, special purpose areas, and critical equipment needs
• Partners with R&D colleagues to ensure laboratory equipment uptime through scheduled equipment maintenance & repair
• Leads and provides hands-on resolution, when required, for the operations, maintenance, and repair of facility support systems in a safe and expeditious manner
• Partners with Safety to maintain up-to-date records for all Authorities Having Jurisdiction (AHJ)
• Define and manage external supplier relationships for utilities maintenance partners and site support services including landlord-tenant issues
• Work with and support shipping and receiving personal
• Perform procurement activities including pre-qualification, negotiating supplier agreements, etc.
• Vendor management, including but not limited to sourcing and overseeing contracts of service providers/vendors for facility functions
• Advising business on measures to improve the efficiency and cost-effectiveness of the facility
• Perform other duties as assigned

Requirements:

• BS degree in engineering or related field or equivalent experience required
• At least 8 years of facility infrastructure & operations management within the biotech/biopharma industry, preferably in an R&D or manufacturing environment
• Demonstrated ability to work and collaborate in cross-functional teams, in a fast pace, dynamic team setting
• Strong interpersonal, verbal, and written communication skills are essential
• Self-motivated, resilient, team leader